“Superior Antiemetic Therapy for Optimal Patient Outcomes”.

Gritrox (Granisetron Hcl) 3 mg/3ml Solution IV Injection/Infusion is highly selective 5-HT3 receptor antagonist used for the prevention and treatment of nausea and vomiting associated with chemotherapy, radiotherapy, surgery and off-label other nausea and vomiting related situation such as gastroparesis, acute gastroenteritis and cyclic vomiting syndrome

Indications:

• Prevention and treatment of acute and delayed nausea & vomiting due to chemotherapy and radiotherapy (CINV & RINV)
• Postoperative nausea and vomiting (PONV)
• Postoperative shivering
• Other nausea & vomiting related situation such as gastroparesis, acute gastroenteritis and cyclic vomiting syndrome.
• In children aged 2 years and above for chemotherapy-induced nausea and vomiting

Pharmaceutical Form:

Clear solution in ampoule: 3 mg / 3 ml (1 mg/ml)

Administration:

• Slow IV injection: Undiluted over 30 seconds
• IV infusion: Dilute to 5 ml per mg and administer over 5 minutes Compatible diluents: 0.9% Sodium Chloride, 5% Dextrose, Ringer’s lactate, 20% Mannitol

Dosage:

AChemotherapy / Radiotherapy-induced nausea & vomiting:
1–3 mg (10–40 mcg/kg) given 5 minutes before start of therapy.
Further doses may be given at least 10 minutes apart.
Maximum: 9 mg / 24 hours

Postoperative nausea & vomiting:
1 mg or 3 mg by slow IV injection.
Maximum: 3 mg / 24 hours

Children (≥2 years): 10–40 mcg/kg (up to 3 mg) as IV infusion over 5 minutes.
Pack Size: 5 Ampoules Per Pack